Dr. Kloppenburg, MD PhD, is Professor of Rheumatology in the Department of Rheumatology at the Leiden University Medical Center. She is a rheumatologist and epidemiologist. Since 2000 she is appointed both at the departments of Rheumatology and of Clinical Epidemiology of the LUMC.
Her research interest includes osteoarthritis with focus on two topics, 1) unravelling underlying pathways in development and progression of osteoarthritis, aimed at inflammatory, metabolic and genetic mechanisms, and 2) optimization of methodology to measure osteoarthritis symptoms and signs, to enable development of disease modifying drugs. She is PI of several cohorts and randomized clinical trials in patients with osteoarthritis. She uses imaging modalities, as radiography, ultrasonography and MR imaging and basic science tools, including immunohistochemistry and metabolomics to characterize and study osteoarthritis patients. She has special interest for hand osteoarthritis.